The use of Veno-Arterial Extracorporeal Membrane Oxygenation (VAThe effect of veno-arterial extracorporeal membrane (ECMO) for immunoadsorption has been shown to be effective in lowering mortality rates in neonatal and paediatric patients suffering from severe sepsis and septic shock. However, the efficacy of this treatment in adult patients with septic shock is debatable. The purpose of this study was to evaluate the potential of VA-ECMO as an immunoadsorption treatment in patients with severe sepsis and septic shock.